Children's Adaptive Deep Brain Stimulation for Epilepsy Trial (CADET) Project
The CADET Project is a series of consecutive clinical device trials that aim to investigate the safety, feasibility and effectiveness of thalamic DBS to treat children with Lennox-Gastaut syndrome.
Determining Epileptogenicity in Focal Cortical Dysplasia (DEpth-FCD)
In collaboration with partners in Zurich, we are looking to use a novel device to measure signals from single nerve cells within lesions of children undergoing surgery for epilepsy. This will allow us to better understand how the cells behave in these lesions to produce epilepsy.
Thalamic Recordings in Children Undergoing SEEG (TRICS)
A project currently in set-up. We seek to systematically record from 3 different areas of the thalamus in children undergoing stereoelectroencephalography (SEEG) as part of their work-up for epilepsy surgery at GOSH.
Advanced 7T MRI for presurgical evaluation in epilepsy surgery
In collaboration with partners across London, we are conducting a study to see whether a more powerful MRI scanner can help better identify lesions causing epilepsy, which can be difficult to spot using current technology.
Structural Brain Network Alterations in Focal Epilepsy
We have conducted research to show that the brains of children with epilepsy are wired differently to those without using diffusion MRI scans. We are looking to improve the management of children by using this information to help plan further management.
research projects
The projects described below give an insight into some of our current ongoing research projects. If you are interested in hearing more about them or participating, please feel free to get in touch via the contact page.